Overview
Glucosamine is a chemical found in the body. Glucosamine supplements are sold as glucosamine sulfate,pharma grade glucosamine hydrochloride, and N-acetyl glucosamine.
Glucosamine is used by the body to make other chemicals that build tendons, ligaments, cartilage, and the fluid that surrounds joints. Joints are cushioned by the fluid and cartilage around them. Taking glucosamine might increase the cartilage and fluid around joints and/or help prevent their breakdown.
People commonly use glucosamine sulfate and glucosamine hydrochloride for osteoarthritis. Glucosamine is also used for joint pain, rheumatoid arthritis, multiple sclerosis, and many other conditions, but there is no good scientific evidence to support these other uses.
Uses & Effectiveness ?
Likely Effective for
Osteoarthritis. Taking glucosamine sulfate by mouth for at least 4 weeks can provide some pain relief and improve function for people with knee osteoarthritis. Products that contain glucosamine hydrochloride do not seem to work as well unless they are taken in combination with other ingredients. Taking glucosamine sulfate doesn't seem to reduce the risk of getting osteoarthritis.
There is interest in using glucosamine for a number of other purposes, but there isn't enough reliable information to say whether it might be helpful.