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Is Gentamicin Sulfate safe for Pets?

Is Gentamicin Sulfate safe for Pets?

Nov 08, 2024

Physical and chemical properties:

Gentamicin Sulfate is white or white crystalline powder, moisture-inducing, easily soluble in water, insoluble in lipids, insoluble in organic solvents, chemically stable, stable to temperature and pH changes, pH of 4% aqueous solution is 4.0 ~ 6.0.

Medication instructions:

Its use in domestic animals is limited due to nephrotoxicity and rare ototoxicity and neuromuscular block. Microbial resistance is of great concern, although many bacteria are resistant to gentamicin and may be sensitive to amikacin. Monitoring of serum levels of gentamicin is recommended if this drug must be used in animals with pre-existing renal dysfunction. The blood concentration of each drug should be less than 2μg/ml. 

Use this class of drugs systemic only when absolutely necessary in older animals or those with impaired kidney function, and with caution in rabbits, birds and reptiles. Rehydration therapy is necessary during reptile treatment. Uric acid levels in birds and reptiles were monitored.

Note:

  1. It has nephrotoxicity and ototoxicity, and should be avoided with other drugs that have nephrotoxicity and ototoxicity.
  2. Avoid use in pregnant animals.
  3. Bacteria are very easy to develop resistance to it, in the process of treatment, to grasp the dose and the cycle of use, reduce or prevent the generation of drug resistance, once resistance occurs immediately after stopping the drug, bacteria can restore sensitivity.
  4. Not for allergic patients.

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